How to use PRS?
False-positive results in diagnostic immunopathology can lead to unnecessary treatments. A study compared HRP conjugates in diagnostic assays, and the results were eye-opening! (Nuovo, 2016)
The findings revealed false positives in 13-36% of cases using commonly used commercial assays based on the HRP conjugate.
But here's where PRS shines!
PRS eliminates false negative/positive staining results with 100% on-slide control.
Our control targets are meticulously tested & calibrated for consistency.
Targets remain as permanent records, allowing future evaluations.
PRS offers a stable shelf life, ensuring reliable results.
PRS provides a quantifiable measure of staining reagents for EVERY slide.
Now, let's talk about how PRS is revolutionizing immunohistochemistry by replacing traditional tissue controls
Replacing Tissue Controls with PRS
Traditional tissue controls often lack consistency and uniformity, leading to subjective interpretations.
PRS steps in with a game-changing solution:
Tissue Control vs. PRS
The Evolution of Quality Control in IHCTraditional tissue controls have long been the standard in immunohistochemistry (IHC), but they come with limitations: lack of standardization, batch-to-batch variability, and the potential for misuse by pathologists.
Here's how PRS revolutionizes quality control:
Traditional Tissue Controls
- Lack of Standardization
Traditional controls vary between batches and sources, making standardization challenging.
- Batch-to-Batch Variability:
Inconsistent results can arise due to variations in control materials.
- Potential Misuse
Pathologists may misinterpret or misuse traditional controls, leading to inaccuracies.
Enter PRS (Process Record Slides):
- Certified ISO 13485 Medical Device
PRS consists of primary and secondary protein targets with known antigen expression levels, certified to meet rigorous medical device standards.
- Standardization
PRS provides reference materials with known properties suitable for examination, ensuring consistent quality.
- 100% Process QC
PRS is used for 100% process quality control for each IHC staining run, guaranteeing accuracy and reproducibility.
How PRS Replaces Tissue Control:
- Standardization
PRS eliminates the variability seen in traditional tissue controls, offering a standardized, reliable alternative.
- Reference Materials
PRS serves as a reference material with known properties, eliminating reliance on previous batches.
- 100% Accuracy
Each #IHC staining run is individually assessed for accuracy, ensuring precise results every time.
- Regulatory Compliance
PRS aids in achieving accreditation and compliance with #ISO 15189, #CLIA, and #CAP standards.
